Science Links to Send to Those Questioning Our Product Safety

On almost a weekly basis there are dichotomous articles that are written about the e-vapor industry. On one hand, scientific reports and consumer testimonials are produced that verify what we have said for years; that e-Vapor products have the science and consumer experience behind them to undeniably state that the products we have made available for years are vastly and incredibly less harmful than tobacco cigarettes. Undeniable. Yet, on a weekly basis journalists write articles stating such as these two lines from the same March 2015 article; “e-cigarettes could have the same relationship to cigarettes as methadone does to heroin.” andThe problem is that the safety claims of e-cigarettes have not been proven.” Really? These horrendous, alarmingly false statements go unchecked and are then carried forward as fact by those who do not take any time to review the completed science categorically refuting such statements. On the same week the above statements were published, a study by the Official Journal of the International Society of Regulatory Toxicology and Pharmacology reported that “e-cigarette products were similar to the study air blanks rather than to deliveries from conventional cigarettes; no significant contribution of cigarette smoke HPHCs from any of the compound classes tested was found for the e-cigarettes.”  Debate over…or now should be.

We at NICMAXX would like to make available to all a list of completed scientific studies on e-Vapor products and hope that you will forward to any journalist or legislative body that makes claims that we are in need of further science or that there is no or not enough science completed on our products to make any determination of whether e-Vapor products are either harmful or safe. We will list the study’s link and it’s conclusion below. This post will be amended as a living document and more science added periodically:

1) Source: The FDA’s “Evaluation of e-Cigarettes”


Conclusion: The report concluded that in one Marlboro tobacco cigarette, there were 11,190 Tobacco Specific Nitrosamines (TSN’s)and in one tested e-Cig cartridge which represents on average 30 tobacco cigarettes, there were 9 TSN’s. 99.992% less. Also, on the FDA’s press release announcing the study’s results on the bottom was the following notation: “Health care professionals and consumers may report serious adverse events (side effects) or product quality problems with the use of e-cigarettes to the FDA’s MedWatch Adverse Event Reporting program either online, by regular mail, fax or phone.” On December 10, 2010 the D.C. Appellate Court that was hearing litigation brought by Smoking Everywhere, noted on its decision that Regarding harm to third parties and to the public’s interest, the district court observed that the FDA had cited no evidence to show that electronic cigarettes harmed anyone”

2) Source: The Journal Regulatory Toxicology and Pharmacology report Comparison of select analytes in aerosol from e-cigarettes with smoke from conventional cigarettes and with ambient air” 


Conclusion“The deliveries of HPHCs tested for these e-cigarette products were similar to the study air blanks rather than to deliveries from conventional cigarettes; no significant contribution of cigarette smoke HPHCs from any of the compound classes tested was found for the e-cigarettes. Thus, the results of this study support previous researchers’ discussion of e-cigarette products’ potential for reduced exposure compared to cigarette smoke.” 

3) Source:  Johns Hopkins Bloomberg School of Public Health. “E-cigarette exposure impairs immune responses in mouse model”


Conclusion: “Cigarette smoke contains 1,014 free radicals per puff. e-cigarette vapor contains far fewer free radicals than cigarette smoke — one percent as much.

4) Source: New England Journal of Medicine Hidden Formaldehyde in E-Cigarette Aerosols”


Conclusion:  The study found that for the e-Vapor product types used by the vast majority of e-cigarette companies, and all of NICMAXX products, that Formaldehyde was “NOT DETECTED” in their peer reviewed study. Said lead Professor David Peyton when critics reviewed his study “It is exceedingly frustrating to me that we are being associated with saying that e-cigarettes are more dangerous than cigarettes-that is a fact not in evidence.

5) Source: American Journal of Preventative Medicine. Which Nicotine Products Are Gateways to Regular Use?”


Conclusion: Hookah and ETPs (electronic tobacco products) are increasingly becoming the first tobacco product ever tried by youth; however, uptake of ETPs is poor, unlike cigarettes and SLT (smokeless tobacco), and does not appear to lead to significant daily/non-daily use of cigarettes and SLT.

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